ATF2, activating transcription factor 2, 1386

N. diseases: 122; N. variants: 17
Disease: Metastatic melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma 		0.010 AlteredExpression disease BEFREE The elevated expression of PKCε in advanced metastatic melanoma results in the increased phosphorylation of the transcription factor ATF2 on threonine 52, which causes its nuclear localization and confers its oncogenic activities. 23589174 2013