|
Adrenal gland hypofunction
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
A CRH test and insulin tolerance test (ITT) may help the he mechanism underlying these possible AIs.
|
31597820 |
2020 |
|
Renal Cell Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results demonstrate a possible involvement of the CRH system and its significance in carcinogenesis of RCC.
|
31721113 |
2020 |
|
Islet Cell Tumor
|
0.010 |
Biomarker
|
disease |
BEFREE |
Ectopic Corticotropin-Releasing Hormone-Secreting Pancreatic Neuroendocrine Tumor: Excellent Response of Liver Metastases to Peptide Receptor Radionuclide Therapy as Demonstrated by 68Ga-DOTATOC and 18F-FDG PET/CT Imaging.
|
31714276 |
2020 |
|
Secondary malignant neoplasm of liver
|
0.010 |
Biomarker
|
disease |
BEFREE |
Ectopic Corticotropin-Releasing Hormone-Secreting Pancreatic Neuroendocrine Tumor: Excellent Response of Liver Metastases to Peptide Receptor Radionuclide Therapy as Demonstrated by 68Ga-DOTATOC and 18F-FDG PET/CT Imaging.
|
31714276 |
2020 |
|
Well Differentiated Pancreatic Endocrine Tumor
|
0.010 |
Biomarker
|
disease |
BEFREE |
Ectopic Corticotropin-Releasing Hormone-Secreting Pancreatic Neuroendocrine Tumor: Excellent Response of Liver Metastases to Peptide Receptor Radionuclide Therapy as Demonstrated by 68Ga-DOTATOC and 18F-FDG PET/CT Imaging.
|
31714276 |
2020 |
|
Acute pancreatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Because little is known about the role of corticotropin-releasing factor (CRF) agonists in regulating responses in pancreatitis, we evaluated the effects of urocortin 2 (UCN2) and stressin1 in caerulein-induced acute pancreatitis (AP) model in rats.
|
31100090 |
2019 |
|
Amyloidosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Stress activates hypothalamic-pituitary adrenal (HPA) axis and releases corticotropin-releasing hormone (CRH) from hypothalamus and in peripheral system, which increases the formation of Aβ, tau hyperphosphorylation, and blood-brain barrier (BBB) disruption in the brain.
|
30837843 |
2019 |
|
anaphylaxis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Compared with WT mice, CRF<sub>2</sub><sup>-/-</sup> mice exhibited greater serum histamine levels and exacerbated IgE-mediated anaphylaxis and colonic permeability.
|
30439403 |
2019 |
|
Malignant tumor of colon
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Chronic Stress, Inflammation, and Colon Cancer: A CRH System-Driven Molecular Crosstalk.
|
31614860 |
2019 |
|
Fatigue
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The meta-analysis also indicated that supervised yoga class had a significant effect on CRF; the six-week program had a moderate beneficial effect while the 60/90 min/session supervised yoga class and the eight-week program demonstrated a large effect on fatigue in patients with breast cancer.
|
31127466 |
2019 |
|
Glioma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The aim of the present study was to investigate the levels of CRF in glioma, and explore the link between CRF and lincRNA-p21 in this disease.
|
29981322 |
2019 |
|
Hyperglycemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Different BG measurements for each patient were collected and recorded in a specific database (e-CRF) in order to analyse the rates of hypo- and hyperglycaemia.
|
30689675 |
2019 |
|
Hypothyroidism
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In the male fish, transcriptions of corticotropin-releasing hormone (crh) and thyroid-stimulating hormone (tsh) in the brain were significantly up-regulated, probably as a compensation for hypothyroidism, but thyroglobulin (tg) and deiodinase 2 (dio2) were down-regulated in thyroid or liver.
|
30508752 |
2019 |
|
Pancreatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Because little is known about the role of corticotropin-releasing factor (CRF) agonists in regulating responses in pancreatitis, we evaluated the effects of urocortin 2 (UCN2) and stressin1 in caerulein-induced acute pancreatitis (AP) model in rats.
|
31100090 |
2019 |
|
Seasonal Affective Disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The following keywords were used: "Seasonal affective disorder", OR "Winter Depression", OR "Seasonal depression" associated with: "HPA Axis" OR "cortisol" OR "CRH" OR "ACTH".
|
31299439 |
2019 |
|
Social Communication Disorder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Corticotropin releasing factor (CRF) is an important neuropeptide activated by social stress, and it contributes to neural and behavioral adaptations, as indicated by impaired social interactions and anhedonic effects.
|
29330004 |
2019 |
|
Acute myocardial infarction
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the association of estimated CRF ( eCRF ) with the risk of first acute myocardial infarction ( AMI ).
|
30991880 |
2019 |
|
Adrenal Cortical Adenoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
As adrenals with bilateral nodular hyperplasia exhibit diffuse CRH immunoreactivity and adrenal cortical adenomas either lack this finding or show few immunoreactive cells, this marker may be useful to distinguish these lesions.
|
30502716 |
2019 |
|
Depression, Postpartum
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Interaction between the functional SNP rs2070951 in NR3C2 gene and high levels of plasma corticotropin-releasing hormone associates to postpartum depression.
|
31388769 |
2019 |
|
Nose symptoms
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Therapeutic indexes include the Visual Analog Scale (VAS) of nasal symptoms and the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) for AR patients; experimental indexes include corticotropin releasing hormone (CRH), adreno-corticotropic hormone (ACTH), cortisol (CORT), interleukin 4 (IL-4), and interferon-γ (IFN-γ).
|
31221225 |
2019 |
|
Interstitial Cystitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Dysregulation of bladder corticotropin-releasing hormone receptor in the pathogenesis of human interstitial cystitis/bladder pain syndrome.
|
31844086 |
2019 |
|
Regular astigmatism - corneal
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
<b>Abbreviations:</b> ICRS: intrastromal corneal ring segments; UDVA: uncorrected distance visual acuity; CDVA: corrected distance visual acuity; logMAR: logarithm of minimum angle of resolution; SE: spherical equivalent; IOP: intra-ocular pressure; Km: mean keratometry; CA: corneal astigmatism; WTR: with-the-rule; ATR: against-the-rule; OBL: oblique; SB: symmetric bow-tie; AB: asymmetric bow-tie; IS: inferior steepening; SRAX: skewed radial axis; Q: asphericity (<i>Q</i>-value); CCT: central corneal thickness; CTP: corneal thinnest point; ORA: ocular response analyzer; CH: corneal hysteresis; CRF: corneal resistance factor; HOAs: higher-orders aberrations; RMS: root mean square; SD: standard deviation; CI: confidence interval.
|
30868919 |
2019 |
|
Ichthyosis Bullosa of Siemens
|
0.010 |
Biomarker
|
disease |
BEFREE |
Electroacupuncture Regulates Disorders of Gut-Brain Interaction by Decreasing Corticotropin-Releasing Factor in a Rat Model of IBS.
|
31737064 |
2019 |
|
Chronic interstitial cystitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Dysregulation of bladder corticotropin-releasing hormone receptor in the pathogenesis of human interstitial cystitis/bladder pain syndrome.
|
31844086 |
2019 |
|
Excessive drinking
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
These results suggest that the CRF<sup>CeA-BNST</sup> pathway could be targeted for the treatment of excessive drinking in alcohol use disorder.
|
30886240 |
2019 |