CRH, corticotropin releasing hormone, 1392

N. diseases: 402; N. variants: 2
Disease: Chorioamnionitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008495
Disease: Chorioamnionitis
Chorioamnionitis 		0.030 AlteredExpression phenotype BEFREE The presence of chorioamnionitis led to exaggerated PGHS2 mRNA responses to IL-1β but diminished effects of CRH. 23666959 2013
CUI: C0008495
Disease: Chorioamnionitis
Chorioamnionitis 		0.030 Biomarker phenotype BEFREE Our findings showed a significant impact of pPROM with chorioamnionitis on placental CRH peptides and receptors, suggesting that placental expression of stress-related pathways is activated in infective process. 21106714 2011
CUI: C0008495
Disease: Chorioamnionitis
Chorioamnionitis 		0.030 GeneticVariation phenotype BEFREE The first set involves chronic and acute psychosocial stressors, psychological distress caused by those stressors, increased secretion of placental corticotropin releasing hormone (CRH), changes in sexual behaviours or enhanced susceptibility to bacterial vaginosis and chorioamnionitis, cigarette smoking or cocaine use, and decidual vasculopathy. 11520404 2001