|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Age (P = 0.24), surgical status (P = 0.95), or sepsis (P = 0.77) did not influence the CRP course.
|
29438222 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The prediction of NLR, an easy, inexpensive, and rapid method, along with CRP in the neonatal period for diagnosis of sepsis, will be more effective in detecting culture-proven sepsis and in decreasing unnecessary antibiotherapy.
|
29055117 |
2018 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
<b>Conclusions:</b> Majority of postpartum cervical discharge, fever, and increased CRP levels do not represent morbid infections and/or sepsis.
|
29671364 |
2019 |
|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Death was the primary outcome in only one study and a survival benefit was not observed in the subset specified as sepsis (10 RCTs; RR, 0.94; 95% CI, 0.85-1.03; I<sup>2</sup> = 0%), those without industry sponsorship (nine RCTs; RR, 0.98; 95% CI, 0.87-1.10; I<sup>2</sup> = 0%), high PCT-guided algorithm adherence (five RCTs; RR, 0.93; 95% CI, 0.71-1.22; I<sup>2</sup> = 0%), and PCT-guided algorithms without C-reactive protein (eight RCTs; RR, 0.96; 95% CI, 0.87-1.06; I<sup>2</sup> = 0%).
|
30772386 |
2019 |
|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Recent National Institute for Health and Care Excellence (NICE) CG149 guidelines suggest considering performing a lumbar puncture (LP) to investigate for meningitis in early-onset sepsis in a neonate when a C-reactive protein (CRP) level >10mg/L, but the evidence for this recommendation is poorly defined.
|
30509228 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Between 2012 and 2015, PCT use among sepsis discharges increased six-fold while lactate and CRP use remained unchanged.
|
30332466 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Circulating concentrations of the sensitive inflammatory marker C-reactive protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and inflammation, when vascular reactivity may be modulated.
|
15795363 |
2005 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Positive post-test probability for any combinations of simultaneously analyzed CRP, PCT and CD64 showed improved diagnostic accuracy for sepsis.
|
28898742 |
2018 |
|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We evaluated the impact of an automatic stop order (ASO) and C-reactive protein (CRP) on the duration of antibiotics and level of intervention in infants screened for early-onset sepsis who had negative cultures.
|
28155332 |
2018 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
At the time of the admission, presepsin, procalcitonin, C-reactive protein, and IL-8 were significantly higher in the sepsis group.
|
31651475 |
2019 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The aim of the present study is to determine the association of melatonin hormone level on CRP, Total Antioxidant Status, Leukocyte, Procalcitonin, and Malondialdehyde, all acute phase reactants in the dark and light cycle of rats with sepsis model.
|
31806239 |
2020 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The levels of hemoglobin, white blood cell, platelet, lactate, and C-reactive protein were measured in the blood samples drawn from the patients with sepsis at diagnosis, at the 48th hour, and on day 7.
|
28167245 |
2017 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The objectives of this study were to study the clinical and biochemical profile of neonates with sepsis and to evaluate the diagnostic role of presepsin and its comparison with C-reactive protein (CRP) and Procalcitonin (PCT).
|
29577181 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Kinetic studies of PCT and CRP can improve sensitivity and accuracy when evaluating the prognosis of patients with sepsis and those with septic shock.
|
30656987 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genetic analysis found that individuals with the polymorphism of the FcγRIIa receptor that binds CRP poorly were also more likely to have decreased monocyte human leukocyte antigen DR and posttraumatic sepsis.
|
26496101 |
2015 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
There were significantly higher serum levels of CRP among late onset versus early onset sepsis group with significantly higher serum levels of hsCRP and presepsin among early onset compared with the late onset sepsis group (p < 0.05 for all).
|
29895470 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
C-reactive protein (CRP) is widely used in early detection of sepsis or organ dysfunction.
|
20552244 |
2010 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The area under ROC curve showed that the clinical accuracy of microRNA-25 for sepsis diagnosis was better than CRP and PCT (AUG=0.806, 0.676 and 0.726, P<0.05).The decrease in level of microRNA-25 was correlated with the severity of sepsis, SOFA score, CRP and PCT level, meanwhile, microRNA-25 level can be used for predicting the prognosis of patients, the patients with microRNA-25 level ≤0.492 had a lower 28 d survival rate.
|
26339334 |
2015 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Six hours of polymicrobial sepsis elicited by cecal ligation and puncture (CLP) elevated serum C-reactive protein (CRP) (a bacteremia and sepsis marker) concentration in anesthetized and mechanically ventilated neonatal pigs.
|
27767365 |
2017 |
|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We performed a systematic review and meta-analysis to evaluate the diagnostic accuracy of neutrophil CD64, comparing it with C-reactive protein (CRP) and procalcitonin (PCT) for the diagnosis of infection in adult patients with septic syndrome, based on sepsis-2 criteria.
|
30623257 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Neonates with clinical manifestations of sepsis who exhibited two positive screening tests (microESR, C- reactive protein, band cell count) were included and randomized into no zinc and zinc group.
|
28891027 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
CRP, IL-6 and PCT are applicable to the differential diagnosis of sepsis and differentiating the sepsis induced by Gram-negative bacteria from Gram-positive bacteria.
|
30004393 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Therefore, the diagnosis of sepsis is often based on the development of clinical signs, in combination with laboratory tests such as a rise in C-reactive protein (CRP).
|
19152691 |
2009 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Serum levels of calprotectin and C-reactive protein were significantly higher in patients with melioidosis and nonmelioidosis sepsis than in healthy controls.
|
28179407 |
2017 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study assessed the ability of mid-regional proadrenomedullin (MR-proADM) in comparison to conventional biomarkers (procalcitonin (PCT), lactate, C-reactive protein) and clinical scores to identify disease severity in patients with sepsis.
|
29562917 |
2018 |