|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Duration of sleep
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.
|
27126917 |
2016 |
|
Leukemia, Mast-Cell
|
0.020 |
Biomarker
|
disease |
BEFREE |
Broadly, patients either have indolent/smoldering SM (ISM/SSM) or advanced SM, the latter includes aggressive SM (ASM), SM with associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL).
|
30536695 |
2019 |
|
Mastocytosis, Systemic
|
0.020 |
Biomarker
|
disease |
BEFREE |
Broadly, patients either have indolent/smoldering SM (ISM/SSM) or advanced SM, the latter includes aggressive SM (ASM), SM with associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL).
|
30536695 |
2019 |
|
Mastocytosis, Systemic
|
0.020 |
Biomarker
|
disease |
BEFREE |
We analyzed cytogenetic and molecular characteristics of 109 patients (KIT D816V+, n = 102, 94%) with indolent (ISM, n = 26) and advanced SM (n = 83) with (n = 73, 88%) or without AHN.
|
29341334 |
2018 |
|
Leukemia, Mast-Cell
|
0.020 |
Biomarker
|
disease |
BEFREE |
This leads to a wide variety of clinical manifestations resulting from excessive mediator release in CM and benign forms of SM (indolent SM, ISM) and from tissue mast cell infiltration causing multiorgan dysfunction and failure in more aggressive subtypes (aggressive SM, ASM, or mast cell leukemia).
|
28775983 |
2017 |
|
Malignant tumor of colon
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
RT-PCR was used to quantify miR-1307-3p and ISM1 expression of colon cancer tissues and cell lines.
|
31513891 |
2019 |
|
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
The authors evaluated the cognitive performance of patients with low-grade glioma (LGG) before and after surgery, and specifically investigated 1) the effects of hemispheric tumor location and 2) the type of surgery (either with or without intraoperative stimulation mapping [ISM]).
|
31731264 |
2019 |
|
Colon Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
RT-PCR was used to quantify miR-1307-3p and ISM1 expression of colon cancer tissues and cell lines.
|
31513891 |
2019 |
|
Low grade glioma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In total, 77 patients with LGG were included (38 and 39 patients with right- and left-sided lesions, respectively; and 42 patients with and 35 patients without ISM).
|
31731264 |
2019 |
|
Liver carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Overall, hsa_circ_0091570 sponge miR-1307 as a ceRNA and regulate ISM1 expression by exerting functional roles in HCC.
|
31207319 |
2019 |
|
Schizophrenia
|
0.010 |
Biomarker
|
disease |
BEFREE |
A phase II study to evaluate the pharmacokinetics, safety, and tolerability of Risperidone ISM multiple intramuscular injections once every 4 weeks in patients with schizophrenia.
|
29112001 |
2018 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
The restricted and high-level expression of cell-surface GRP78 on cancer cells and cancer ECs make them uniquely susceptible to ISM-targeted apoptosis.
|
24464222 |
2014 |
|
Malignant neoplasm of stomach
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our results suggest that the effect of H19 in GC is mediated by the direct upregulation of ISM1 and the indirect suppression of CALN1 expression via miR-675.
|
24810858 |
2014 |
|
Stomach Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our results suggest that the effect of H19 in GC is mediated by the direct upregulation of ISM1 and the indirect suppression of CALN1 expression via miR-675.
|
24810858 |
2014 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
The restricted and high-level expression of cell-surface GRP78 on cancer cells and cancer ECs make them uniquely susceptible to ISM-targeted apoptosis.
|
24464222 |
2014 |