PARP1, poly(ADP-ribose) polymerase 1, 142

N. diseases: 565; N. variants: 23
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.340 Biomarker disease BEFREE PJ34, a PARP1 inhibitor, promotes endothelial repair in a rabbit model of high fat diet-induced atherosclerosis. 31276434 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.340 Biomarker disease BEFREE Autophagy and poly(ADP-ribose) polymerase 1 (PARP-1) are activated and involved in a series of cell processes under oxidative stress, which is associated with pathogenesis of atherosclerosis. 30394268 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.340 Biomarker disease BEFREE These results demonstrated that PARP-1 offers a promising therapeutic target for endothelial dysfunction and atherosclerosis. 30158868 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.340 Biomarker disease BEFREE Nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP-1) is associated with the inflammation response during atherosclerosis. 23085506 2013
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.340 Biomarker disease CTD_human Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content. 19124646 2009