PARP1, poly(ADP-ribose) polymerase 1, 142

N. diseases: 565; N. variants: 23
Disease: Cardiac fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis 		0.020 Biomarker disease BEFREE In CFs, preincubation with PARP1 or mTOR inhibitors all blocked TGF-β1 induced cardiac fibrosis. 29278652 2019
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis 		0.020 Biomarker disease BEFREE PARP-1 inhibition attenuates cardiac fibrosis induced by myocardial infarction through regulating autophagy. 30041821 2018