MAPK14, mitogen-activated protein kinase 14, 1432

N. diseases: 626; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333463
Disease: Senile Plaques
Senile Plaques
0.030 Biomarker disease BEFREE Inhibition of p38 MAPK in the present study protected SH-SY5Y cells from the toxicity of Aβ<sub>1-42</sub>, and alleviated the formation of senile plaques and cognitive impairment in AD mice. 29201176 2017
CUI: C0333463
Disease: Senile Plaques
Senile Plaques
0.030 Biomarker disease BEFREE Strong active SAPK/JNK and p38 immunoreactivity has been observed restricted to neurons and glial cells containing hyperphosphorylated tau, as well as in dystrophic neurites of senile plaques in AD. 15977985 2005
CUI: C0333463
Disease: Senile Plaques
Senile Plaques
0.030 Biomarker disease BEFREE Strong active SAPK/JNK and p38 immunoreactivity has been observed restricted to neurons and glial cells containing hyperphosphorylated tau, as well as in dystrophic neurites of senile plaques in AD. 15658002 2004