MAPK14, mitogen-activated protein kinase 14, 1432

N. diseases: 626; N. variants: 7
Disease: Neuropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0442874
Disease: Neuropathy
Neuropathy 		0.110 GeneticVariation group GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
CUI: C0442874
Disease: Neuropathy
Neuropathy 		0.110 AlteredExpression group BEFREE Exenatide-induced phosphorylation of p38 and CREB was also totally blocked by the PKA inhibitor and siRNA/p38<i>β</i>, but not by siRNA/p38<i>α</i> Seven-day intrathecal injections of siRNA/p38<i>β</i> (but not siRNA/p38<i>α</i>) completely blocked exenatide-induced spinal p38 activation, <i>β</i>-endorphin expression, and mechanical antiallodynia in rats with established neuropathy, although siRNA/p38<i>β</i> and siRNA/p38<i>α</i> were not antiallodynic. 28202578 2017