MAPK14, mitogen-activated protein kinase 14, 1432

N. diseases: 626; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis
0.020 Biomarker disease BEFREE Overall, the crosstalk between extracellular signal-related kinase (ERK) 1/2 and p38 MAPK signalling has been shown to regulate various physiological functions, including central nervous system, cardiac fibrosis, alcoholic cardiac fibrosis, osteoclast differentiation, mucin production in the airway, vascular smooth muscle cell migration, steroidogenesis and asthmatic inflammation. 30884895 2019
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis
0.020 Biomarker disease BEFREE FO prevented cardiac fibrosis associated with DM and decreased cardiac transforming growth factor beta-1and p38 MAP kinases. 29615288 2018