MAPK14, mitogen-activated protein kinase 14, 1432

N. diseases: 626; N. variants: 7
Disease: Destructive Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2348101
Disease: Destructive Arthritis
Destructive Arthritis 		0.010 AlteredExpression disease BEFREE Although previous data have established a role for c-Jun N-terminal kinase (JNK) and extracellular signal-related kinase (ERK) in different animal models of arthritis, most recent data indicate that the stable activation of p38 MAPK and in part of ERK significantly contributes to destructive arthritis in mice transgenic for human tumour necrosis factor-alpha. 16207342 2005