CSF2, colony stimulating factor 2, 1437

N. diseases: 1028; N. variants: 7
Disease: Melanoma, B16 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004565
Disease: Melanoma, B16
Melanoma, B16 		0.060 Biomarker disease BEFREE Silencing of Foxp3 enhances the antitumor efficacy of GM-CSF genetically modified tumor cell vaccine against B16 melanoma. 28176947 2017
CUI: C0004565
Disease: Melanoma, B16
Melanoma, B16 		0.060 Biomarker disease BEFREE This study investigated the effect of exogenous granulocyte-macrophage colony-stimulating factor on the growth of B16 melanoma, S180 sarcoma, and U14 cervical carcinoma in mice. 28240048 2017
CUI: C0004565
Disease: Melanoma, B16
Melanoma, B16 		0.060 Biomarker disease BEFREE Testing of 5l in mice demonstrated pharmacodynamic inhibition of IDO, as measured by decreased kynurenine levels (>50%) in plasma and dose dependent efficacy in mice bearing GM-CSF-secreting B16 melanoma tumors. 19507862 2009
CUI: C0004565
Disease: Melanoma, B16
Melanoma, B16 		0.060 AlteredExpression disease BEFREE Granulocyte-macrophage colony-stimulating factor (GM-CSF) cDNA in a nonviral expression vector was inserted into MDA-MB-231 (human breast cancer), M21 (human melanoma), B16 (murine melanoma), and P815 (mastocytoma) cells by particle-mediated gene transfer. 10078967 1999
CUI: C0004565
Disease: Melanoma, B16
Melanoma, B16 		0.060 Biomarker disease BEFREE Effective immunization against the murine B16 melanoma by a nonviral approach in which a gene gun is used to transfer GM-CSF cDNA into tumor cells has been described. 9625251 1998
CUI: C0004565
Disease: Melanoma, B16
Melanoma, B16 		0.060 Biomarker disease BEFREE Transduction of B16 melanoma cells with the GM-CSF gene rendered the cells more immunogenic. 9455809 1998