CSF2, colony stimulating factor 2, 1437

N. diseases: 1028; N. variants: 7
Disease: Kidney Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 Biomarker disease BEFREE Macrophage elimination or GM-CSF neutralization protected against acute kidney injury in mice, and increased GM-CSF was detected in urine of patients infected by hlyA-positive UPEC. 31719643 2020
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 AlteredExpression disease BEFREE Active expression of erythropoietin receptor (EPOR) was not identified in renal cells by lineage tracing study, whereas expression of colony-stimulating factor 2 receptor β (CSF2Rβ) was identified in kidney macrophages and upregulated after AKI. 30414800 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 AlteredExpression disease BEFREE Multiple chemokines/cytokines, IL-3, IL-6, IL-15, IL-18, leukemia inhibitory factor, macrophage colony-stimulating factor, macrophage inflammatory protein-2, granulocyte-macrophage colony-stimulating factor, and monocyte chemotactic protein-1 were significantly increased in AKI vs. sham kidneys. 18753296 2008