|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
The concentrations of matrix metalloproteinase 9 (MMP-9), MMP-2, tissue inhibitor of metalloproteinase 1 (TIMP-1), and TIMP-2 were significantly elevated in the lumbar CSF samples, and we found interesting dynamics for MMP-9 that offer novel insight into its role in pediatric patients with tuberculous meningitis.
|
30753686 |
2020 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Abbreviations:</b> ART: anti-retroviral therapy; Child PIP: Child Healthcare Problem Identification Programme; CCF: congestive cardiac failure; CNS: central nervous system; CoNS: coagulase-negative <i>staphylococci</i>; CSF: cerebrospinal fluid; DNA pcr: deoxyribonucleic acid polymerase chain reaction; ETAT: emergency triage assessment and treatment; LMIC: low- and middle-income countries; MDG: Millennium Development Goals; MRI: magnetic resonance imaging; MRSA: methicillin-resistant <i>Staphylococcus aureus</i>; NAI: non-accidental injury; NTS: non-typhi salmonella; PJP: <i>Pneumocystis jiroveci</i> pneumonia; PSHD: presumed severe HIV disease; QECH: Queen Elizabeth Central Hospital; RHD: rheumatic heart disease; RTA: road traffic accident; TB: tuberculosis; TBM: tuberculous meningitis; WHO: World Health Organization; SAM: severe acute malnutrition.
|
30451103 |
2019 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
Three of which were also showed significantly different between TBM and VM in CSF samples (<i>n</i> = 70, <i>P</i> < 0.05).
|
31572691 |
2019 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
The association between PZA dose and exposures in plasma and CSF provides a rationale to study higher PZA doses for TBM.
|
31202922 |
2019 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
To retrospectively analyze the data of 72 patients with tuberculous meningitis (TBM) combined with cranial nerve palsy, to explore the incidence, clinical features, CSF assay changes and outcome in patients with TBM.
|
31336359 |
2019 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
CSF protein concentration associated with ventriculoperitoneal shunt obstruction in tuberculous meningitis.
|
29914605 |
2018 |
|
Tuberculosis, Meningeal
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We found that HIV infection, diabetes mellitus, duration of symptoms <14 days, radiologic findings of hydrocephalus, and CSF ADA level >10 IU were associated with TBM.
|
29705393 |
2018 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
Performance of nested RT-PCR on CSF for tuberculous meningitis diagnosis in HIV-infected patients.
|
28911358 |
2017 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
CM patients had lower counts of WBC in CSF, lower total protein in CSF and serum CD4/CD8 ratio than TBM patients (P < 0.05).
|
28068915 |
2017 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
Asparagine is associated with the removal of increased nitrites in the brain, whereas elevated proline coincides with the classic biochemical marker of increased CSF protein in TBM.
|
29018323 |
2017 |
|
Tuberculosis, Meningeal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We used <sup>1</sup>H nuclear magnetic resonance-based metabolomics to investigate the metabolic features of the CSF from 18 TBM and 20 VM patients.
|
28063937 |
2017 |
|
Tuberculosis, Meningeal
|
0.100 |
Biomarker
|
disease |
BEFREE |
Patients with scrub typhus meningitis had a lower CSF white blood-cell count (WBC) than the TBM group (130.8±213 195±175 cells/mm<sup>3</sup>, P=0.002), lower CSF protein elevation (125±120 vs. 195.2±108.2mg/dl, P=0.002), and higher CSF sugar (70.1±32.4 vs. 48.7±23.4mg/dl, P=0.006).
|
29078126 |
2017 |