CSF3, colony stimulating factor 3, 1440

N. diseases: 687; N. variants: 4
Disease: Malignant transformation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 GeneticVariation phenotype BEFREE Patients with poor neutrophil response despite high doses of granulocyte colony-stimulating factor (G-CSF) are at greatest risk for malignant transformation. 22080845 2012
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 GeneticVariation phenotype BEFREE The potential adverse effects of G-CSF administration, particularly the risk of malignant transformation, have fueled ongoing debates, some of which can only be settled in follow-up studies extending over several decades. 20237318 2010
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 AlteredExpression phenotype BEFREE G-CSF/G-CSFR expression in some bladder cancers appears to be an early event during malignant transformation that increases beta1-integrin expression and adhesion and thereby may promote tissue invasion. 14751388 2004