|
Neutrophilia (disorder)
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Under controlled conditions of experimental ischemia-reperfusion and unilateral ureteral obstruction injuries in mice, renal G-CSF mRNA and protein expression significantly increased and systemic neutrophilia developed.
|
31509227 |
2020 |
|
Neutrophilia (disorder)
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Interleukin-1β (IL-1β) modulates the expression of granulocyte colony-stimulating factor (G-CSF), a cytokine that promotes cancer-associated neutrophilia and NET generation.
|
31552036 |
2019 |
|
Neutrophilia (disorder)
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
A 76-year-old woman presented with neutrophilia at a medical check-up and thorough examination revealed a high level of serum G-CSF.
|
30286731 |
2018 |
|
Neutrophilia (disorder)
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CRTC2 knockout mice that express one CRTC3 allele (CRTC2/3m mice) develop neutrophilia and splenomegaly in adulthood due to the up-regulation of granulocyte-colony stimulating factor (G-CSF); these effects are reversed following administration of neutralizing anti-G-CSF antiserum.
|
29078378 |
2017 |
|
Neutrophilia (disorder)
|
0.100 |
Biomarker
|
disease |
BEFREE |
CSL324 was effective in controlling G-CSF-mediated neutrophilia when administered either before or after G-CSF.
|
28515226 |
2017 |
|
Neutrophilia (disorder)
|
0.100 |
Biomarker
|
disease |
BEFREE |
Deficiency of PI3-Kinase catalytic isoforms p110γ and p110δ in mice enhances the IL-17/G-CSF axis and induces neutrophilia.
|
28724384 |
2017 |
|
Neutrophilia (disorder)
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We report, for the first time, the occurrence of a SETBP1 mutation in two cases, as well as changes in G-CSF and IL-6 in SETBP1 wild type vs. mutated patients that are supportive of a hypothesis that neutrophilia associated with plasma cell neoplasms may sometimes be reactive and may sometimes represent a second clonal entity.
|
26389776 |
2016 |
|
Neutrophilia (disorder)
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we provide evidence to support EGCG's capacities in stimulating G-CSF production and neutrophilia in vivo.
|
26293782 |
2015 |
|
Neutrophilia (disorder)
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The reduced airway neutrophilia in OVA-challenged Tie2-hABCA1 mice was associated with significant decreases in G-CSF protein levels in pulmonary vascular endothelial cells, alveolar macrophages, and BALF.
|
24813055 |
2014 |
|
Neutrophilia (disorder)
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The IL-22R1 transgenic animals developed neutrophilia that correlated with increased levels of circulating IL-17 and granulocyte colony-stimulating factor.
|
20971950 |
2011 |
|
Neutrophilia (disorder)
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, IL-17E induces G-CSF production in vitro and mIL-17E-transgenic mice had increased serum G-CSF and exhibit neutrophilia, a property shared by IL-17.
|
11714825 |
2001 |
|
Neutrophilia (disorder)
|
0.100 |
Biomarker
|
disease |
BEFREE |
Intriguingly, peripheral blood neutrophilia and progenitor cell mobilisation responses to G-CSF were also significantly influenced.
|
10764151 |
2000 |
|
Neutrophilia (disorder)
|
0.100 |
Biomarker
|
disease |
BEFREE |
Factors other than overproduction of G-CSF and extensive neutrophilia could be required for the development of neutrophil-mediated acute and chronic tissue damage.
|
10843738 |
2000 |
|
Neutrophilia (disorder)
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, in vivo treatment of gcsfr-Delta715 mice with G-CSF results in increased production of neutrophils leading to a sustained neutrophilia.
|
9989983 |
1999 |