IL34, interleukin 34, 146433

N. diseases: 103; N. variants: 5
Disease: Tumor Progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.020 Biomarker phenotype BEFREE In this context CSF1R, the cellular receptor for colony stimulating factor-1 (CSF1) and interleukin 34 (IL-34), occupies a central role in manipulating the behavior of TAMs and the dysregulation of CSF1R signaling has been implicated in cancer progression and immu-nosuppression in many specific cancers. 31215373 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.020 AlteredExpression phenotype BEFREE High co-expression of IL-34 and M-CSF correlates with tumor progression and poor survival in lung cancers. 29323162 2018