CSRP1, cysteine and glycine rich protein 1, 1465

N. diseases: 32; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.320 Biomarker disease BEFREE The MYLK, KLK2, KLK3, HAN11, LTF, CSRP1 and TGM4 genes presented significant changes in their functional connectivity between normal and tumoral conditions and were also classified as the top seven most informative genes for the prostate cancer genesis process by our discriminant analysis. 19055846 2008
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.320 Biomarker disease BEFREE Androgen induction of the androgen receptor coactivator four and a half LIM domain protein-2: evidence for a role for serum response factor in prostate cancer. 17975004 2007
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.320 Biomarker disease CTD_human Global analysis of differentially expressed genes in androgen-independent prostate cancer. 17199135 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker disease PSYGENET One of the genes suggested to play an important role in the pathophysiology of bipolar disorder (BPD) is PDLIM5, which encodes LIM domain protein. 23031404 2012
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker disease BEFREE One of the genes suggested to play an important role in the pathophysiology of bipolar disorder (BPD) is PDLIM5, which encodes LIM domain protein. 23031404 2012
CUI: C0014173
Disease: Endometrial Hyperplasia
Endometrial Hyperplasia
0.300 Biomarker disease CTD_human Hormonally active doses of isoflavone aglycones promote mammary and endometrial carcinogenesis and alter the molecular tumor environment in Donryu rats. 22248470 2012
CUI: C0349578
Disease: Complex Endometrial Hyperplasia
Complex Endometrial Hyperplasia
0.300 Biomarker disease CTD_human Hormonally active doses of isoflavone aglycones promote mammary and endometrial carcinogenesis and alter the molecular tumor environment in Donryu rats. 22248470 2012
CUI: C0349579
Disease: Atypical Endometrial Hyperplasia
Atypical Endometrial Hyperplasia
0.300 Biomarker disease CTD_human Hormonally active doses of isoflavone aglycones promote mammary and endometrial carcinogenesis and alter the molecular tumor environment in Donryu rats. 22248470 2012
CUI: C0456483
Disease: Simple Endometrial Hyperplasia
Simple Endometrial Hyperplasia
0.300 Biomarker disease CTD_human Hormonally active doses of isoflavone aglycones promote mammary and endometrial carcinogenesis and alter the molecular tumor environment in Donryu rats. 22248470 2012
CUI: C0746402
Disease: manic symptom
manic symptom
0.300 Biomarker phenotype PSYGENET Peripheral PDLIM5 expression in bipolar disorder and the effect of olanzapine administration. 23031404 2012
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker group CTD_human Global analysis of differentially expressed genes in androgen-independent prostate cancer. 17199135 2007
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.030 Biomarker disease BEFREE Here, we investigated the association of elevated CRP (≥1 vs. <1 mg/dL) with (i) recurrence of HCC and (ii) OS after liver transplantation (LT). 31141535 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.030 Biomarker disease BEFREE Here we have shown that the LIM domain protein Enigma directly interacts with MDM2 to form a ternary complex with p53 in vitro and in human hepatoma and colon carcinoma cell lines and mouse embryonic fibroblasts. 21060154 2010
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.030 PosttranslationalModification disease LHGDN CAV1 and CSRP1 were inactivated in HCC by aberrant methylation and they may serve as important biomarkers of malignancy. 17341888 2006
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.030 Biomarker disease BEFREE CAV1 and CSRP1 were inactivated in HCC by aberrant methylation and they may serve as important biomarkers of malignancy. 17341888 2006
Confluent and Reticulate Papillomatosis
0.020 Biomarker disease BEFREE In this study, we described novel preferential bindings of 25-hydroxycholesterol (25HOCh) to CRP1-7 compared with other lipids and explored the antiviral effects of both 25HOCh and CRP1-7 against spring viremia carp virus (SVCV) infection in zebrafish. 30653529 2019
Confluent and Reticulate Papillomatosis
0.020 Biomarker disease BEFREE Confirming those expectations, in vitro neutralization and in vivo protection against spring viremia carp virus (SVCV) infections were demonstrated by crp2-6/CRP2-6 using crp1-7 transfected and/or CRP1-7-enriched supernatant-treated fish cells and crp2-5-injected one-cell stage embryo eggs, respectively. 28915434 2017
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.020 GeneticVariation disease BEFREE As an example, IG-SVM achieved a classification accuracy of 90.32% for colon cancer, which is difficult to be accurately classified, only based on three genes including CSRP1, MYL9, and GUCA2B. 29246519 2017
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.020 Biomarker disease BEFREE Here we have shown that the LIM domain protein Enigma directly interacts with MDM2 to form a ternary complex with p53 in vitro and in human hepatoma and colon carcinoma cell lines and mouse embryonic fibroblasts. 21060154 2010
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 Biomarker group BEFREE By database searching, CSRP1 was hypothesized to be a colorectal cancer related tumor suppressor gene. 19187582 2008
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.020 Biomarker disease BEFREE The MYLK, KLK2, KLK3, HAN11, LTF, CSRP1 and TGM4 genes presented significant changes in their functional connectivity between normal and tumoral conditions and were also classified as the top seven most informative genes for the prostate cancer genesis process by our discriminant analysis. 19055846 2008
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.020 Biomarker disease BEFREE Androgen induction of the androgen receptor coactivator four and a half LIM domain protein-2: evidence for a role for serum response factor in prostate cancer. 17975004 2007
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 Biomarker group BEFREE The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein. 11420696 2001
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.010 Biomarker disease BEFREE SelP was significantly proportionally correlated with CRP 1 (R = 0.762, P < 0.0001) and 3 days (R = 0.777 P < 0.0001) following AMI. 30889044 2020
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker disease BEFREE Though LIM-domain protein AJUBA was identified as a putative oncogene, the function and underlying mechanisms of AJUBA in cervical cancer remain largely unknown. 29126926 2018