CST6, cystatin E/M, 1474

N. diseases: 72; N. variants: 1
Disease: Mammary Tumorigenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1512981
Disease: Mammary Tumorigenesis
Mammary Tumorigenesis 		0.020 PosttranslationalModification phenotype BEFREE Cystatin M is a secreted inhibitor of lysosomal cysteine proteases and increasing evidences indicate that it is a novel target for epigenetic silencing during mammary tumorigenesis. 20004178 2010
CUI: C1512981
Disease: Mammary Tumorigenesis
Mammary Tumorigenesis 		0.020 PosttranslationalModification phenotype BEFREE In summary, this study establishes that the tumor suppressor cystatin M is a novel target for epigenetic silencing during mammary tumorigenesis and that this aberrant event can occur before development of invasive breast cancer. 16912163 2006