Disease: Malignant Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.020 Biomarker group BEFREE Alternative polyadenylation (APA) site-switching of 3'UTRs is prevalent in NSCLC, and CSTF2 may serve as an oncogene regulates the 3'UTR length of cancer related genes in NSCLC. 31391087 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.020 Biomarker group BEFREE Our findings also suggest a CSTF2-regulated <i>RAC1</i>-3'UTR shortening program as an exploitable therapeutic strategy for patients with UCB.<b>Significance:</b> These findings demonstrate that the short isoform of <i>RAC1</i> is critical in UCB tumorigenesis and may have implications for developing new therapeutic strategies to treat this disease.<i>Cancer Res; 78(20); 5848-62.©2018 AACR</i>. 30143523 2018