Disease: Rheumatoid Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 AlteredExpression disease BEFREE In addition, CTGF was determined as a direct target gene of miR-26a, and upregulation of miR-26a inhibited CTGF expression in cartilage tissues of RA rats. 31267533 2020
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 Biomarker disease BEFREE Significant elevation of synovial fluid CTGF concentration was found in RA patients, demonstrating excellent diagnostic ability to predict RA (area under the curve (AUC) = 0.97). 29166915 2017
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 Biomarker disease BEFREE Inhibition of angiogenesis by arsenic trioxide <i>via</i> TSP-1-TGF-β1-CTGF-VEGF functional module in rheumatoid arthritis. 29088724 2017
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 AlteredExpression disease BEFREE For the chondrocytes from OA and RA treated with 5-Aza, the mRNA expression level of TRAF1 and CTGF was highly increased (p < 0.05). 28470428 2017
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 Biomarker disease BEFREE We have previously shown that the inhibition of connective tissue growth factor (CTGF) is a potential therapeutic strategy against rheumatoid arthritis (RA). 28682648 2017
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 AlteredExpression disease BEFREE CTGF was overexpressed in serum and SF samples from RA patients compared with samples from normal controls. 27044368 2016
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 Biomarker disease BEFREE We have shown that connective tissue growth factor (CTGF) plays an important role in the pathogenesis of rheumatoid arthritis (RA). 25352179 2015
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 Biomarker disease BEFREE Connective tissue growth factor, a regulator related with 10-hydroxy-2-decenoic acid down-regulate MMPs in rheumatoid arthritis. 21850473 2012
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 Biomarker disease CTD_human Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. 19192274 2009
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.390 AlteredExpression disease BEFREE Additionally, CTGF was up-regulated in this experimental model of RA. 16869004 2006