Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.270 Biomarker disease BEFREE Our objective was to determine the role of CTGF/CCN2 as a predictor of cardiovascular events in type 2 diabetes in the Veterans Affairs Diabetes Trial (VADT) cohort. 29382658 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.270 Biomarker disease BEFREE Immune cytokine TGF-β1 combined with cattle encephalon glycoside and ignotin injection could improve the contents of CTGF, HO-1 and NT-3, and be better to treat the peripheral neuropathy of type 2 diabetes. 29259937 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.270 PosttranslationalModification disease BEFREE Correlation of CTGF gene promoter methylation with CTGF expression in type 2 diabetes mellitus with or without nephropathy. 24676352 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.270 Biomarker disease BEFREE Urine CTGF was positively associated with plasma CTGF in both type 2 diabetes (p = 0.0005) and controls (p = 0.01). 24192280 2013
Diabetes Mellitus, Non-Insulin-Dependent
0.270 GeneticVariation disease BEFREE The CTGF -945 G/C polymorphism (rs6918698) was examined in 495 Caucasian subjects with type 2 diabetes. 22533709 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.270 GeneticVariation disease BEFREE We studied the effect of a common CTGF polymorphism rs9493150 on the risk of the T2DM development in three independent German cohorts. 22045431 2011
Diabetes Mellitus, Non-Insulin-Dependent
0.270 Biomarker disease RGD Peroxisome proliferator-activated receptor-gamma activation attenuates cardiac fibrosis in type 2 diabetic rats: the effect of rosiglitazone on myocardial expression of receptor for advanced glycation end products and of connective tissue growth factor. 19902320 2010
Diabetes Mellitus, Non-Insulin-Dependent
0.270 AlteredExpression disease BEFREE Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes. 17554073 2007