Disease: Osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE CCN2 inhibition may represent a new therapeutic concept in osteosarcoma. 30317661 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE Moreover, FAK, PI3K, Akt and NF-κB activation were also shown to be involved in CTGF-mediated osteosarcoma metastasis. 29909077 2018
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE Similarly, GSK-LSD1 inhibited proliferation and CTGF expression in mesenchymal cells, including myoepithelial cells and osteosarcoma cells. 29088714 2017
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE However, the effect of CTGF on Angpt2 regulation and angiogenesis in human osteosarcoma remains largely unknown. 28108312 2017
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells. 26707502 2016
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE In conclusion, the differentially expressed IGFBP4, HOXC8, LMO4, MDK, and CTGF genes may be involved in MeCP2 gene-mediated proliferation and apoptosis in osteosarcoma cells. 25613065 2015
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE Our data indicated that downregulation of miR-26b in osteosarcoma elevated the levels of CTGF and Smad1, facilitating osteosarcoma metastasis. 25761878 2015
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE Here, we found that CCN2 was upregulated in human osteosarcoma cells after treatment with cisplatin. 24637722 2014
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE MicroRNA (miRNA) analysis of CTGF-overexpressed osteosarcoma versus control cells probed mechanisms of CTGF-mediated promotion of migration. 25003330 2014
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE CCN1 and CCN2 expression shows no prognostic relevance in osteosarcoma. 18245529 2008
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease LHGDN Expression of CCN1, CCN2, and CCN3 was measured by quantitative PCR in 45 newly diagnosed osteosarcomas. 18245529 2008