IL23R, interleukin 23 receptor, 149233

N. diseases: 306; N. variants: 49
Disease: Arteriosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 Biomarker disease BEFREE Therefore, the use of IL-23 or IL-23R is a potential therapeutic approach for treating inflammatory diseases, including atherosclerosis. 30328797 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 Biomarker disease BEFREE These data demonstrate that loss of IL-23R does not affect development of experimental atherosclerosis in LDLr-deficient mice, despite a role for IL-23 in differentiation of IL-17-producing T cells. 29618473 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 GeneticVariation disease BEFREE We compared normal subjects and patients with atherosclerosis in terms of the R381Q variant of the IL-23R gene as a functional single-nucleotide polymorphism (SNP). 26261042 2015
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 Biomarker disease BEFREE As a key element in the T-helper 17 (Th17) cell-mediated inflammatory process, interleukin-23 receptor (IL-23R) may play a crucial role in the pathogenesis of atherosclerosis. 25192515 2014