PDIK1L, PDLIM1 interacting kinase 1 like, 149420

N. diseases: 138; N. variants: 1
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE Our findings indicate that CD163 contributes to gliomagenesis via CK2 and provides preclinical evidence that CD163 and the CD163 pathway might serve as a therapeutic target for glioma. 30258108 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE These findings demonstrate how IFNγ induced CK2 regulates RIG-I to drive a complex program of metabolic adaptation and redox homeostasis, crucial for determining glioma cell fate. 26631910 2017
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE Likewise, apigenin and siRNA-induced depletion of CK2 failed to sensitize glioma cells to the cytotoxic effect of 2 to 10 G-rays of γ irradiation, as assessed by clonogenic assays. 22614258 2012
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE CK2-Is and CK2 small interfering RNA (siRNA) reduced glioma cell viability, inhibited TNFα-mediated NF-κB activation, and sensitized cell to TNFα-induced apoptosis. 22318540 2012