CTNNB1, catenin beta 1, 1499

N. diseases: 1368; N. variants: 68
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018923
Disease: Hemangiosarcoma
Hemangiosarcoma
0.310 GeneticVariation disease BEFREE Aberrant expression of p53, inactivation of cell cycle inhibitors, loss of beta-catenin, and increased VEGFR1 were more frequent in AS. 31252633 2019
CUI: C0018923
Disease: Hemangiosarcoma
Hemangiosarcoma
0.310 Biomarker disease CTD_human Our data indicated that p53 and beta-catenin mutations in the o-nitrotoluene-induced hemangiosarcomas and K-ras mutations and p53 protein expression in riddelliine-induced hemangiosarcomas most likely occurred as a result of the genotoxic effects of these chemicals. 13678655 2003