CTNNB1, catenin beta 1, 1499

N. diseases: 1368; N. variants: 68
Disease: Myocardial Ischemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.330 AlteredExpression disease BEFREE Increased nuclear β-catenin interacting with T-cell factor 4 (TCF4) affects the expression of target genes including SCN5A in ischemic heart disease, which is characterized by frequent ventricular tachycardia/fibrillation. 31419437 2019
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.330 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.330 AlteredExpression disease BEFREE Taken together, these data indicate that AR suppresses acute activation of β-catenin and, thereby, blocks consequent induction of mesenchymal markers during early reperfusion after myocardial ischemia. 29190815 2017
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.330 Biomarker disease BEFREE Arrhythmia susceptibility in mice after therapy with beta-catenin-transduced hematopoietic progenitor cells after myocardial ischemia/reperfusion. 19602881 2009