Esophageal carcinoma
|
0.200 |
Biomarker
|
disease |
BEFREE |
Epigenetic deregulations of Wnt/β-catenin and transforming growth factor beta-Smad pathways in esophageal cancer: Outcome of DNA methylation.
|
30880778 |
2019 |
Esophageal carcinoma
|
0.200 |
Biomarker
|
disease |
BEFREE |
AT‑101 induces G1/G0 phase arrest via the β‑catenin/cyclin D1 signaling pathway in human esophageal cancer cells.
|
30483745 |
2019 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
The effect of TIPE2 overexpression on the Wnt/β-catenin signaling pathway was evaluated by detecting the protein levels of β-catenin, c-Myc and cyclinD1 in EC9076 cells and xenograft tumors of esophageal carcinoma.
|
29343267 |
2018 |
Esophageal carcinoma
|
0.200 |
Biomarker
|
disease |
BEFREE |
Our results demonstrated that RARα knockdown suppressed the tumorigenicity of EC via Wnt/β-catenin pathway.
|
30155836 |
2018 |
Esophageal carcinoma
|
0.200 |
Biomarker
|
disease |
BEFREE |
Pin1 is a critical therapeutic and preventive target in esophageal cancer because of its positive regulation of β-catenin and cyclin D1.
|
28325828 |
2017 |
Esophageal carcinoma
|
0.200 |
GeneticVariation
|
disease |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Our study elucidates a mechanism of NDRG1-regulated Wnt pathway activation and EMT via affecting TLE2 and β-catenin expression in esophageal cancer cells.
|
27414086 |
2016 |
Esophageal carcinoma
|
0.200 |
Biomarker
|
disease |
BEFREE |
Loss of LKB1 expression may result in the deregulation of WNT/β-catenin pathway to promote malignant progression of esophageal cancer.
|
24022664 |
2014 |
Esophageal carcinoma
|
0.200 |
Biomarker
|
disease |
BEFREE |
These results suggested that PKCι positively regulated β-catenin through negatively regulated autophagy and depletion of PKCι promoted apoptosis via autophagic degradation of β-catenin in esophageal cancer cells.
|
23359356 |
2014 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Inhibition of EC Eca-109 cellproliferation by down-regulating β-catenin expression could improve cell ultrastructure by mediating blockade in G0/G1 through inhibiting cyclin D1, PCNA and the MAPK pathway (p-ERK1/2).
|
22938416 |
2012 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
The purpose of this study is to test whether inhibition of beta-catenin or overexpression of p53 can decrease survivin expression and render esophageal cancer cells more susceptible to apoptosis.
|
20236666 |
2010 |
Esophageal carcinoma
|
0.200 |
Biomarker
|
disease |
BEFREE |
LEF1 and CTNNB1 may be the important genes causing the esophageal cancer cell radioresistance.
|
20868558 |
2010 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Expression level of beta-catenin is associated with prognosis of esophageal carcinoma.
|
17552014 |
2007 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Four (8%) esophageal cancer tissues showed high nuclear beta-catenin staining.
|
17309796 |
2007 |
Esophageal carcinoma
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
beta-Catenin splice variants and downstream targets as markers for neoplastic progression of esophageal cancer.
|
16114033 |
2005 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
We hypothesized that down-regulation of beta catenin would inhibit the growth of human esophageal cancer.
|
14752418 |
2004 |
Esophageal carcinoma
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Interrelation between expression of matrix metalloproteinase 7 and beta-catenin in esophageal cancer.
|
12498294 |
2002 |