CTNNB1, catenin beta 1, 1499

N. diseases: 1368; N. variants: 68
Disease: HPV positive oropharyngeal squamous cell carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2828150
Disease: HPV positive oropharyngeal squamous cell carcinoma
HPV positive oropharyngeal squamous cell carcinoma 		0.020 AlteredExpression disease BEFREE We evaluated the expression of p16 and β-catenin (nuclear and membrane) by immunohistochemistry staining in 101 OPSCC tissues and HPV status by HPV DNA in situ hybridization. 26493274 2016
CUI: C2828150
Disease: HPV positive oropharyngeal squamous cell carcinoma
HPV positive oropharyngeal squamous cell carcinoma 		0.020 Biomarker disease BEFREE The results showed that the membrane weighted index of β-catenin was inversely correlated with p16 positivity (P < .001) and lymph node metastasis (P = .026), whereas nuclear staining of β-catenin was associated with p16-positive OPSCC (P < .001). 25209444 2015