CTNNB1, catenin beta 1, 1499

N. diseases: 1368; N. variants: 68
Disease: Immunosuppression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.020 Biomarker disease BEFREE In non-neoplastic immune cells, upregulated Wnt/β-catenin is, however, associated with either immunosuppression or immunostimulation. 30886380 2019
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.020 Biomarker disease BEFREE These results indicate that Wnt/β-catenin pathways in human melanoma may be involved in immunosuppression and immunoresistance in both induction and effector phases of antitumor immunoresponses partly through IL-10 production, and they may be attractive targets for restoring immunocompetence in patients with Wnt/β-catenin-activated melanoma. 22815287 2012