CTSB, cathepsin B, 1508

N. diseases: 304; N. variants: 17
Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE In conclusion, bortezomib may induce ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors. 25375375 2014
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE The role of the urokinase-type plasminogen activator receptor (uPAR) and cathepsin B in stem-like phenotype has been extensively studied in several solid tumors. 22573309 2012
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE The diagnostic and prognostic significance of cathepsin B (CTSB) and L (CTSL) is well documented for solid tumors. 20567828 2010