CTSD, cathepsin D, 1509

N. diseases: 242; N. variants: 13
Disease: Creutzfeldt-Jakob disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022336
Disease: Creutzfeldt-Jakob disease
Creutzfeldt-Jakob disease 		0.030 GeneticVariation disease BEFREE We conclude that the CTSD position 224 polymorphism alone is not a significant risk or disease-modifying factor in sporadic or genetic CJD. 19571726 2010
CUI: C0022336
Disease: Creutzfeldt-Jakob disease
Creutzfeldt-Jakob disease 		0.030 Biomarker disease BEFREE In recent studies, cathepsin D was co-localized with PrP(Sc), the disease-associated form of the prion disease, and abnormal expression of cathepsin D correlated with tissue damage in brains of sporadic Creutzfeldt-Jakob disease (CJD). 19828951 2009
CUI: C0022336
Disease: Creutzfeldt-Jakob disease
Creutzfeldt-Jakob disease 		0.030 GeneticVariation disease LHGDN Cathepsin D SNP associated with increased risk of variant Creutzfeldt-Jakob disease. 18426579 2008