Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.050 PosttranslationalModification disease BEFREE Two hundred and sixty samples with available frozen cell pellets including 70 randomly selected cases of negative for intraepithelial lesion or malignancy (NILM)&HPV-negative, 70 randomly selected cases of NILM&HPV-positive, and 120 cytologic abnormalities & HPV-positive from a population-based cervical cancer screening program (n = 7,604) were investigated for the DNA methylation pattern of CADM1, FAM19A4, and MAL. 30608989 2019
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.050 PosttranslationalModification disease BEFREE These results indicate that a negative FAM19A4/miR124-2 methylation assay result is likely to rule out the presence of cervical cancer. 31390052 2019
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.050 PosttranslationalModification disease BEFREE Within screening round capability of FAM19A4/mir124-2 methylation to detect cervical cancer was 100% (11/11, 95% CI: 71.5-100). 29663363 2018
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.050 PosttranslationalModification disease BEFREE (3)There were no significant differences of FAM19A4 methylation in different clinicopathological parameters of cervical cancer. 30486875 2018
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.050 PosttranslationalModification disease BEFREE Recently, DNA methylation analysis of FAM19A4 in cervical scrapes has been shown to adequately detect high-grade cervical intraepithelial neoplasia and cervical cancer (≥ CIN3) in high-risk HPV (hrHPV)-positive women. 26317579 2016