BTLA, B and T lymphocyte associated, 151888

N. diseases: 74; N. variants: 6
Disease: B-Cell Lymphomas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.020 GeneticVariation group BEFREE TNFRSF14, encoding the receptor HVEM, is frequently mutated in germinal center (GC)-derived B cell lymphomas.In this issue, Mintz et al. demonstrate that the HVEM-BTLA axis restrains T cell help to GC B cells. 31433965 2019
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.020 AlteredExpression group BEFREE BTLA was strongly expressed in chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL, 19 of 19 positive) when compared with other small B-cell lymphomas, including follicular lymphoma (0 of 24 positive), mantle cell lymphoma (0 of 10 positive), and marginal zone lymphoma (0 of 5 positive). 19762537 2009