CX3CR1, C-X3-C motif chemokine receptor 1, 1524

N. diseases: 310; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.030 Biomarker disease BEFREE Further analysis of protein expression changes revealed a reduction in CX3CR1 (CX3C chemokine receptor 1) in microglial VPS35-deficient cortex after ischemic stroke, implicating CX3CR1 as a potential cargo of VPS35 in this event. 31771656 2019
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.030 GeneticVariation disease BEFREE We investigated effects of selective deletion of microglial Nhe1 in Cx3cr1-Cre<sup>ER</sup> ;Nhe1<sup>f/f</sup> mice on neuroinflammation and tissue repair after ischemic stroke. 30043461 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.030 GeneticVariation disease BEFREE In this study, we investigated the risk of ischemic stroke associated with fractalkine receptor CX3CR1 polymorphisms. 15644279 2005