|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis.
|
28474233 |
2017 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The CYBA gene (⁎)49A>G polymorphism modifies the risk of coronary artery disease.
|
27314008 |
2016 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of C242T and A640G in CYBA gene and the risk of coronary artery disease: a meta-analysis.
|
24392120 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population.
|
24415302 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 years old), determined their genotypes regarding glutamate-cysteine ligase modifier subunit (GCLM) C-588T, manganese superoxide dismutase (SOD2) Val16Ala, endothelial nitric oxide synthase (NOS3) G894T, NAD(P)H oxidase p22phox (CYBA) C242T, and myeloperoxidase (MPO) G-463A polymorphisms, and prospectively evaluated the association between these polymorphisms and CHD events.
|
24933031 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The A640G polymorphism in the NAD(P)H oxidase p22phox gene (CYBA) is associated with risk reduction of coronary heart disease: a meta-analysis.
|
24345348 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Relationship of the p22phox (CYBA) gene polymorphism C242T with risk of coronary artery disease: a meta-analysis.
|
24039708 |
2013 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of nicotinamide adenine dinucleotide phosphate oxidase p22phox gene 549C>T polymorphism with coronary artery disease.
|
22613645 |
2012 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The CYBA gene A640G polymorphism influences predispositions to coronary artery disease through interactions with cigarette smoking and hypercholesterolemia.
|
21777168 |
2011 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of p22phox gene C242T polymorphism with coronary artery disease: a meta-analysis.
|
20100625 |
2010 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Insight into the role of CYBA A640G and C242T gene variants and coronary heart disease risk. A case-control study.
|
18324526 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
C242T polymorphism of NADPH oxidase p22phox and recurrence of cardiovascular events in coronary artery disease.
|
18239158 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Insight into the role of CYBA A640G and C242T gene variants and coronary heart disease risk. A case-control study.
|
18324526 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Associations of polymorphism of P22(phox) C242T, plasma levels of vitamin E, and smoking with coronary heart disease in China.
|
17383305 |
2007 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The 242T variant of the CYBA gene polymorphism increases the risk of coronary artery disease associated with cigarette smoking and hypercholesterolemia.
|
17627182 |
2007 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
C242T polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucasian Italians.
|
16788250 |
2006 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study.
|
16923427 |
2006 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The C242T variant of the CYBA gene encoding the p22phox subunit of the NAD(P)H oxidase, a major source of superoxide production, has been shown to be associated with coronary artery disease and with vascular superoxide production in human veins ex vivo.
|
12639216 |
2003 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Blood pressure is partly controlled by O(-)(2) production by NADPH/NADH oxidase and recently it was shown that a C242T substitution in the p22phox gene was associated with coronary artery disease, in which elevated blood pressure and oxidative stress are also important pathophysiologic features.
|
12037698 |
2002 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Recently, it has been suggested that the C242T polymorphism of the NADH/NADPH oxidase p22 phox gene can reduce susceptibility to coronary artery disease.
|
11133215 |
2001 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The genetic analysis of the p22 phox gene by restriction fragment length polymorphism (RFLP) for control subject and patients with coronary artery disease revealed that the prevalence of the TC + TT genotype of the C242T polymorphism of the p22 phox gene in control subjects was significantly more frequent than in coronary artery disease patients, indicating that the mutation of the p22 phox gene might reduce the susceptibility for coronary artery disease, which is independent of other coronary risk factors.
|
10865844 |
2000 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function.
|
10440830 |
1999 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The p22 phox codon 72 polymorphism is not associated with the risk of CHD in the present samples of Asian Indians and Chinese.
|
10583446 |
1999 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our observations allow the assumption that the p22 phox A640G gene polymorphism is independently associated with the presence and extent of coronary artery disease.
|
10488959 |
1999 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
NADH/NADPH oxidase p22 phox C242T polymorphism and coronary artery disease in the Australian population.
|
10469162 |
1999 |