ADRB2, adrenoceptor beta 2, 154

N. diseases: 53; N. variants: 1
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated 		0.510 Biomarker group CTD_human Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. 11986409 2002
CUI: C0004096
Disease: Asthma
Asthma 		0.500 Biomarker disease CTD_human
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Biomarker phenotype CTD_human The beta2 adrenergic receptor Gln27Glu polymorphism affects insulin resistance in patients with heart failure: possible modulation by choice of beta blocker. 19034036 2008
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease CTD_human beta2-adrenergic receptor polymorphisms and salbutamol-stimulated energy expenditure. 15687340 2005
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.350 Biomarker disease CTD_human Interestingly, beta(2)-AR mRNA was strongly down-regulated by androgen ablation therapy of prostate cancer patients. 18454446 2008
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.340 Biomarker disease CTD_human Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 17003101 2007
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.330 Biomarker group CTD_human Assessment of systemic adverse reactions induced by ophthalmic beta-adrenergic receptor antagonists. 11436944 2001
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.330 Biomarker disease CTD_human Diminished responsiveness of Gs-coupled receptors in severely failing human hearts: no difference in dilated versus ischemic cardiomyopathy. 9554809 1998
CUI: C1623038
Disease: Cirrhosis
Cirrhosis 		0.330 Biomarker disease CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.310 Biomarker disease CTD_human The objective of this study was to determine whether alleles in ADRB2 are associated with diagnosis of autism in the Autism Genetic Resource Exchange (AGRE) population. 17199132 2007
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.310 Biomarker disease CTD_human beta-Blockade and increased dyslipidemia in patients bearing Glu27 variant of beta2 adrenergic receptor gene. 16027735 2005
CUI: C0020621
Disease: Hypokalemia
Hypokalemia 		0.310 Biomarker phenotype CTD_human Debrisoquine phenotype and the pharmacokinetics and beta-2 receptor pharmacodynamics of metoprolol and its enantiomers. 1848636 1991
CUI: C0020621
Disease: Hypokalemia
Hypokalemia 		0.310 Biomarker phenotype CTD_human The influence of the AA 16 beta 2-adrenoceptor polymorphism on systemic and airway responses in asthma. 17292646 2008
CUI: C0020621
Disease: Hypokalemia
Hypokalemia 		0.310 Biomarker phenotype CTD_human Beta-2-adrenoceptor-mediated hypokalemia and its abolishment by oxprenolol. 2826064 1987
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.310 Biomarker group CTD_human Hormonal regulation of beta2-adrenergic receptor level in prostate cancer. 18454446 2008
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.310 Biomarker group CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0001849
Disease: AIDS Dementia Complex
AIDS Dementia Complex 		0.300 Biomarker disease CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.300 Biomarker phenotype CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.300 Biomarker group CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.300 Biomarker group CTD_human Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma. 21245421 2011
CUI: C0033141
Disease: Cardiomyopathies, Primary
Cardiomyopathies, Primary 		0.300 Biomarker group CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0036529
Disease: Myocardial Diseases, Secondary
Myocardial Diseases, Secondary 		0.300 Biomarker group CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.300 Biomarker group CTD_human Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 17003101 2007
CUI: C0040822
Disease: Tremor
Tremor 		0.300 Biomarker phenotype CTD_human Role of central nicotinic and beta-adrenergic receptors in the onset and further development of tail-tremor induced by repeated nicotine administration to rats. 9151294 1997
CUI: C0040822
Disease: Tremor
Tremor 		0.300 Therapeutic phenotype CTD_human Effect of beta-adrenergic receptor antagonists on nicotine-induced tail-tremor in rats. 7902979 1993