ADRB2, adrenoceptor beta 2, 154

N. diseases: 53; N. variants: 1
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated 		0.510 Biomarker group CTD_human Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. 11986409 2002
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Biomarker phenotype CTD_human The beta2 adrenergic receptor Gln27Glu polymorphism affects insulin resistance in patients with heart failure: possible modulation by choice of beta blocker. 19034036 2008
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease CTD_human beta2-adrenergic receptor polymorphisms and salbutamol-stimulated energy expenditure. 15687340 2005
CUI: C0004096
Disease: Asthma
Asthma 		0.500 Biomarker disease CTD_human
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.350 Biomarker disease CTD_human Interestingly, beta(2)-AR mRNA was strongly down-regulated by androgen ablation therapy of prostate cancer patients. 18454446 2008
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.340 Biomarker disease CTD_human Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 17003101 2007
CUI: C1623038
Disease: Cirrhosis
Cirrhosis 		0.330 Biomarker disease CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.330 Biomarker group CTD_human Assessment of systemic adverse reactions induced by ophthalmic beta-adrenergic receptor antagonists. 11436944 2001
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.330 Biomarker disease CTD_human Diminished responsiveness of Gs-coupled receptors in severely failing human hearts: no difference in dilated versus ischemic cardiomyopathy. 9554809 1998
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.320 Biomarker disease PSYGENET However, as the ADRB2 gene product directly interacts with the CACNA1C gene product, and is known to be implicated in BD susceptibility, we conclude that further exploration of the relationships between ADRB2 and BD needs to be undertaken. 22628130 2012
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.310 Biomarker group CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0020621
Disease: Hypokalemia
Hypokalemia 		0.310 Biomarker phenotype CTD_human The influence of the AA 16 beta 2-adrenoceptor polymorphism on systemic and airway responses in asthma. 17292646 2008
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.310 Biomarker group CTD_human Hormonal regulation of beta2-adrenergic receptor level in prostate cancer. 18454446 2008
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.310 Biomarker disease CTD_human The objective of this study was to determine whether alleles in ADRB2 are associated with diagnosis of autism in the Autism Genetic Resource Exchange (AGRE) population. 17199132 2007
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.310 Biomarker disease CTD_human beta-Blockade and increased dyslipidemia in patients bearing Glu27 variant of beta2 adrenergic receptor gene. 16027735 2005
CUI: C0020621
Disease: Hypokalemia
Hypokalemia 		0.310 Biomarker phenotype CTD_human Debrisoquine phenotype and the pharmacokinetics and beta-2 receptor pharmacodynamics of metoprolol and its enantiomers. 1848636 1991
CUI: C0020621
Disease: Hypokalemia
Hypokalemia 		0.310 Biomarker phenotype CTD_human Beta-2-adrenoceptor-mediated hypokalemia and its abolishment by oxprenolol. 2826064 1987
CUI: C0001849
Disease: AIDS Dementia Complex
AIDS Dementia Complex 		0.300 Biomarker disease CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.300 Biomarker group CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C0206019
Disease: HIV Encephalopathy
HIV Encephalopathy 		0.300 Biomarker disease CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C0243010
Disease: Viral Encephalitis
Viral Encephalitis 		0.300 Biomarker group CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C0936243
Disease: HIV-1-Associated Cognitive Motor Complex
HIV-1-Associated Cognitive Motor Complex 		0.300 Biomarker disease CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C4505456
Disease: HIV Coinfection
HIV Coinfection 		0.300 Biomarker disease CTD_human β-Adrenergic receptor gene expression in HIV-associated neurocognitive impairment and encephalitis: implications for MOR-1K subcellular localization. 27400929 2016
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.300 Biomarker phenotype CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0033141
Disease: Cardiomyopathies, Primary
Cardiomyopathies, Primary 		0.300 Biomarker group CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014