Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Impact of interaction between CYP1A1 genetic polymorphisms and smoking on coronary artery disease in the Han of China. 28513235 2017
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 Biomarker disease BEFREE Gene-gene interaction between PPARG and CYP1A1 gene on coronary artery disease in the Chinese Han Population. 28415751 2017
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Han of China. 25189712 2014
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Lack of association between CYP1A1 T6235C polymorphism and coronary artery disease: evidence from a meta-analysis. 23229202 2013
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE 1.The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer. 19650794 2010
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Polymorphisms of cytochrome P450 1A1, cigarette smoking and risk of coronary artery disease. 19563927 2009
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and susceptibility to smoking-related coronary artery disease: a case-only study. 17408703 2007
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE We found that individuals with CYP1A1 CC genotype had a more than three fold increase in risk for severe coronary atherosclerosis when they smoked. 15696395 2005
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Through population studies, we have learned that certain CYP1A1 variants, such as Mspl polymorphism, may render the carriers more susceptible to cigarette-induced lung cancer or severe coronary atherosclerosis. 12704594 2003
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes. 11996959 2002