Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 Biomarker disease BEFREE The data indicate that CYP2A6 may have important roles in human colorectal tumorigenesis and progression, so that it could be a candidate therapeutic and chemopreventive target for colorectal cancers. 17683511 2007
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 Biomarker disease CTD_human The data indicate that CYP2A6 may have important roles in human colorectal tumorigenesis and progression, so that it could be a candidate therapeutic and chemopreventive target for colorectal cancers. 17683511 2007
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 GeneticVariation disease BEFREE In case-control comparisons, subjects in the medium and high tertiles of CYP2A6 activity had an increased risk of colorectal cancer compared with subjects with low activity. 11927498 2002
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 Biomarker disease BEFREE Dietary nitrosamines, which are bioactivated by CYP2A6, represent another potential etiologic factor for colorectal cancer. 12505289 2002