Disease: Parkinson Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.010 Biomarker disease BEFREE In the present study, we show the effects of a single dose of Atremorine (5 g, p. o.) on plasma dopamine (DA) response and brain function in PD (n = 183) and the influence that pathogenic (<i>LRRK2</i>), metabolic (<i>CYP2D5, CYP2C9, CYP2C19, CYP3A5, NAT2</i>), transporter (<i>ABCB1</i>), pleiotropic (<i>APOE</i>), and detoxifying genes (<i>CYP1B1, GSTT1, GSTP1, GSTM1, SOD2</i>) involved in the pharmacogenetic network exerts on Atremorine-induced DA response. 31559607 2019