GRK2, G protein-coupled receptor kinase 2, 156

N. diseases: 159; N. variants: 2
Disease: Heart Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		0.030 Biomarker group BEFREE As GRK2 has emerged as drug target in heart disease, we focus on its role in IAV infection and show that it is required for viral uncoating. 30206219 2018
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		0.030 AlteredExpression group BEFREE However GRK2 is a ubiquitous molecule and its kinase activity and scaffold properties brought to several investigations which have evidenced its involvement in pathophysiology of extra-cardiac diseases. 22229580 2012
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		0.030 AlteredExpression group BEFREE This difference, better than an increased expression of GRK2 (not observed in IC), determines the lower LVEF in IC and DC vs. NINDC. 22685168 2012