Disease: Carcinoma breast stage IV ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV 		0.040 Biomarker disease BEFREE CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines. 30411242 2019
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV 		0.040 Biomarker disease BEFREE We selected patients treated with tamoxifen (40 mg per day) for hormone receptor-positive MBC from whom a blood sample for pharmacogenetic analysis (CYP2D6*3, *4, *5, *6, *10 and *41) was available. 20700120 2010
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV 		0.040 GeneticVariation disease BEFREE Our findings do suggest that the presence of two CYP2D6*4 alleles does not exclude a durable response of tamoxifen in metastatic breast cancer. 19597703 2009
CUI: C0278488
Disease: Carcinoma breast stage IV
Carcinoma breast stage IV 		0.040 GeneticVariation disease BEFREE Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer. 17761971 2007