In summary, we propose that FBXO16 functions as a putative tumor suppressor by forming an SCF<sup>FBXO16</sup> complex that targets nuclear β-catenin in a unique manner for ubiquitination and subsequent proteasomal degradation to prevent malignancy.
In summary, we propose that FBXO16 functions as a putative tumor suppressor by forming an SCF<sup>FBXO16</sup> complex that targets nuclear β-catenin in a unique manner for ubiquitination and subsequent proteasomal degradation to prevent malignancy.
In summary, we propose that FBXO16 functions as a putative tumor suppressor by forming an SCF<sup>FBXO16</sup> complex that targets nuclear β-catenin in a unique manner for ubiquitination and subsequent proteasomal degradation to prevent malignancy.