FBXO16, F-box protein 16, 157574

N. diseases: 7; N. variants: 0
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 Biomarker group BEFREE In summary, we propose that FBXO16 functions as a putative tumor suppressor by forming an SCF<sup>FBXO16</sup> complex that targets nuclear β-catenin in a unique manner for ubiquitination and subsequent proteasomal degradation to prevent malignancy. 30714168 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 Biomarker group BEFREE Next, we show that FBXO16 functions as a tumor suppressor in GBM. 30530053 2019