FBXO16, F-box protein 16, 157574

N. diseases: 7; N. variants: 0
Disease: Primary malignant neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.010 Biomarker group BEFREE In summary, we propose that FBXO16 functions as a putative tumor suppressor by forming an SCF<sup>FBXO16</sup> complex that targets nuclear β-catenin in a unique manner for ubiquitination and subsequent proteasomal degradation to prevent malignancy. 30714168 2019