Disease: Sjogren's Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD Aromatase controls Sjögren syndrome-like lesions through monocyte chemotactic protein-1 in target organ and adipose tissue-associated macrophages. 25447050 2015
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease BEFREE In SS, steroid sulphatase was weak and deranged, 3beta- and 17beta-HSD had lost their strict basal acinar cell localization and 5alpha-reductase was mainly found in the cytoplasm of the acinar cells, whereas aromatase showed similar staining in SS and controls. qRT-PCR of labial salivary glands disclosed all corresponding enzyme mRNAs with the levels of 3beta-HSD in SS being the lowest. 19298523 2009
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome. 15314222 2004
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD Aromatase-deficient (ArKO) mice have reduced blood pressure and baroreflex sensitivity. 15178650 2004
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease BEFREE Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome. 15314222 2004
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate gland. 11356695 2001
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD An age-related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene. 10875266 2000
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene. 10393934 1999
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. 9618522 1998
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.220 Biomarker disease MGD Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene. 9826549 1998