Crohn Disease
|
0.400 |
Biomarker
|
disease |
CTD_human |
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
|
17554261 |
2007 |
Crohn's disease of large bowel
|
0.300 |
Biomarker
|
disease |
CTD_human |
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
|
17554261 |
2007 |
Crohn's disease of the ileum
|
0.300 |
Biomarker
|
disease |
CTD_human |
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
|
17554261 |
2007 |
Regional enteritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
|
17554261 |
2007 |
IIeocolitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
|
17554261 |
2007 |
Ulcerative Colitis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Among these loci, we identified variants in 3p21.31, NKX2-3 and CCNY as susceptibility factors for both diseases, whereas variants in PTPN2, HERC2 and STAT3 were associated only with ulcerative colitis in our sample collection.
|
18438405 |
2008 |
Ulcerative Colitis
|
0.400 |
Biomarker
|
disease |
CTD_human |
Among these loci, we identified variants in 3p21.31, NKX2-3 and CCNY as susceptibility factors for both diseases, whereas variants in PTPN2, HERC2 and STAT3 were associated only with ulcerative colitis in our sample collection.
|
18438405 |
2008 |
Ulcerative Colitis
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
Among these loci, we identified variants in 3p21.31, NKX2-3 and CCNY as susceptibility factors for both diseases, whereas variants in PTPN2, HERC2 and STAT3 were associated only with ulcerative colitis in our sample collection.
|
18438405 |
2008 |
Crohn Disease
|
0.400 |
Biomarker
|
disease |
CTD_human |
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
|
18438405 |
2008 |
Crohn Disease
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
|
18438405 |
2008 |
Crohn's disease of large bowel
|
0.300 |
Biomarker
|
disease |
CTD_human |
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
|
18438405 |
2008 |
Crohn's disease of the ileum
|
0.300 |
Biomarker
|
disease |
CTD_human |
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
|
18438405 |
2008 |
Regional enteritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
|
18438405 |
2008 |
IIeocolitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
|
18438405 |
2008 |
Ulcerative Colitis
|
0.400 |
Biomarker
|
disease |
CTD_human |
We also show that several risk loci are common to ulcerative colitis and Crohn's disease (IL23R, IL12B, HLA, NKX2-3 and MST1), whereas autophagy genes ATG16L1 and IRGM, along with NOD2 (also known as CARD15), are specific for Crohn's disease.
|
18438406 |
2008 |
Crohn Disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
We also show that several risk loci are common to ulcerative colitis and Crohn's disease (IL23R, IL12B, HLA, NKX2-3 and MST1), whereas autophagy genes ATG16L1 and IRGM, along with NOD2 (also known as CARD15), are specific for Crohn's disease.
|
18438406 |
2008 |
Crohn Disease
|
0.400 |
Biomarker
|
disease |
CTD_human |
We also show that several risk loci are common to ulcerative colitis and Crohn's disease (IL23R, IL12B, HLA, NKX2-3 and MST1), whereas autophagy genes ATG16L1 and IRGM, along with NOD2 (also known as CARD15), are specific for Crohn's disease.
|
18438406 |
2008 |
Crohn's disease of large bowel
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
|
18438406 |
2008 |
Crohn's disease of the ileum
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
|
18438406 |
2008 |
Regional enteritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
|
18438406 |
2008 |
IIeocolitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
|
18438406 |
2008 |
Ulcerative Colitis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
By contrast, variation in the gene encoding the interleukin-23 (IL-23) receptor subunit, as well as in the IL12B, STAT3 and NKX2-3 gene regions, is associated with both Crohn's disease and ulcerative colitis.
|
18500230 |
2008 |
Crohn Disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
By contrast, variation in the gene encoding the interleukin-23 (IL-23) receptor subunit, as well as in the IL12B, STAT3 and NKX2-3 gene regions, is associated with both Crohn's disease and ulcerative colitis.
|
18500230 |
2008 |
Crohn Disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Positive association of genetic variants in the upstream region of NKX2-3 with Crohn's disease in Japanese patients.
|
18936107 |
2009 |
Carcinoma, Neuroendocrine
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, chemokine C-X-C motif ligand 14 (CXCL14) and NK2 transcription factor related locus 3 Drosophila (NKX2-3) are expressed to a lower level in liver metastases than in primary tumors and normal enterochromaffin cells, which implies a role in neuroendocrine carcinoma differentiation.
|
18953328 |
2009 |