DAB1, DAB adaptor protein 1, 1600

N. diseases: 81; N. variants: 43
Disease: Cognition Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders 		0.020 Biomarker group BEFREE Notable genes in the region are PCSK9, haploinsufficiency of which caused low LDL cholesterol plasma levels in the patient, and DAB1, which is a candidate gene for cognitive deficits, microcephaly, and cerebral abnormalities such as ventriculomegaly and agenesis of the corpus callosum. 26061568 2015
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders 		0.020 AlteredExpression group BEFREE Reductions in Reelin protein and mRNA and Dab 1 mRNA and elevations in Reln receptor VLDLR mRNA demonstrate impairments in the Reelin signaling system in autism, accounting for some of the brain structural and cognitive deficits observed in the disorder. 15820235 2005