DAB1, DAB adaptor protein 1, 1600

N. diseases: 81; N. variants: 43
Disease: Disorientation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233407
Disease: Disorientation
Disorientation 		0.010 AlteredExpression phenotype BEFREE By in utero electroporation, we show that expression of Dab1 isoforms missing exons 7 and 8 or retaining exons 9bc in WT neurons resulted in neuronal migration defects with attenuated Dab1 tyrosine phosphorylation, disrupted leading process extension, and disorientated multipolar neurons in the multipolar accumulation zone. 28968791 2018